Unveiling the Power of Microbial Signatures in Disease Diagnosis, Monitoring & Treatment
Time: 11:00 am
day: Day Two Track A (AM)
Details:
- To better diagnose, understand and treat diseases that includes a microbial compound, an accurate picture of the microbial signature associated with the disease is required
- To analyze microbial cell free DNA in liquid biopsy samples a novel approach was developed that targets “genus-level” bacterial markers, enabling universal sequencing and analysis of bacteria at higher sensitivity and lower cost than deep sequencing of cell free DNA
- This approach was successfully validated in a retrospective study on blood plasma samples of IBD patients and allowed to predict clinical events where the fecal calprotectin levels and disease indexes (Mayo-6, SCDAI) failed
