Decoding Bidirectional Host-Microbiota Interactions to Engineer Synthetic Mucins & Improve Live Biotherapeutic Engraftment
- Examining host mechanisms regulating microbiota through mucosal barrier signaling to identify key interactions governing microbial behavior and community composition
- Investigating how microbiota degrade and interact with mucus signals to understand bidirectional communication pathways driving healthy and dysbiotic microbiome states
- Leveraging synthetic mucin technology to re-engineer host-microbiota signaling and improve live biotherapeutic engraftment and phenotypic modulation at mucosal sites