Chris Weidenmaier
Seminars
Tuesday 24th June 2025
Panel Discussion: Scaling Up Manufacturing for Clinical Trials of LBPs
3:30 pm
- Scaling up LBP production from preclinical to late-stage clinical trial quantities by maintaining microbial consistency, stability, and product quality at larger scales
- Managing the supply chain and logistics for late-stage trials by ensuring reliable and timely delivery of LBPs, including temperature-sensitive storage, transportation, and distribution to multiple clinical sites
- Navigating regulatory requirements during late-stage trials by balancing manufacturing compliance with the strict demands for clinical-grade products and preparing for commercialization
Tuesday 24th June 2025
A Platform for Rationally Designing and Controlled Manufacturing of Complex Consortia Products that combine the Functional Diversity and Activity of Healthy Microbiomes with Scalable, Consistent and MoA-targeted Consortia
1:30 pm
- Enabling precise identification and quantification of individual strains within complex consortia, allowing for potency assessment and process control in manufacturing
- Addressing co-culture challenges by stabilizing microbial communities through rational product design and advanced fermentation strategies
- Ensuring scalability, reproducibility, and quality control of high-diversity microbial therapeutics
- Strategically integrating strain-specific mechanisms with host-microbiome interactions
