Causal Effect Relationship Between Stress Induced Depression in Alzheimer’s Disease (AD) Progression Through Single Bacteria Modulating Regulatory T cell (Treg) and Th17 cells (Th17) Immunity

Time: 4:30 pm
day: Day One – Track B – 3


• Role of T cell regulation of IL-15 and IL-17 in the attenuation of Segmented Filamentous Bacteria (SFB) mediated cognitive deterioration through mitigation of mechanism associated to
anxiety and depression
• Investigation of the role of IL-17a production in the gut lamina propria in the regulation of Th17 responses in the meningeal compartment of SFB mice
• Translational studies to alleviates anxiety and depression in SFB positive mice through modulation of adaptiveimmunity, implications for novel AD therapies